{"id":153,"date":"2021-04-18T22:29:58","date_gmt":"2021-04-18T13:29:58","guid":{"rendered":"http:\/\/cbel.jp\/wp9835259570\/?p=153"},"modified":"2021-04-24T00:05:18","modified_gmt":"2021-04-23T15:05:18","slug":"01-01-10","status":"publish","type":"post","link":"http:\/\/cbel.jp\/en\/01-01-10\/","title":{"rendered":"A bioethical discussion of issues inherent to mitochondrial replacement and having \u201cthree genetic parents\u201d"},"content":{"rendered":"<p><strong>Tomohide Ibuki<br \/>\n<\/strong>Volume 1 Issue 1 Pages 50-62<br \/>\nFirst Published: September 28, 2018<\/p>\n<p style=\"text-align: right;\"><a href=\"http:\/\/cbel.jp\/wp9835259570\/wp-content\/uploads\/2021\/04\/cbel-report_01_01_10_ibuki.pdf\">PDF<\/a><\/p>\n<hr \/>\n<h4>Abstract<\/h4>\n<p>In February 2015, the U.K. became the first nation in the world to legalize the so-called \u201cmitochondrial replacement\u201d procedure for egg cells of patients with mitochondrial disease. Given the possibility that Japan may also seek approval to use this technology, the present study aimed to organize thoughts and discussion points put forth by previous studies concerning the ethical aspects of mitochondrial replacement technology. One main consideration presented here pertains to the unique bioethical issue created by this technology; namely, the birth of children with \u201cthree genetic parents.\u201d I have added my thoughts and discussion points.<\/p>\n<p>With regard to mitochondrial replacement technology, I conclude that the following four issues should be taken into consideration: 1) safety, 2) the likelihood of further application, 3) the child\u2019s identity, and 4) \u201cthree genetic parents.\u201d This paper takes a particularly close look at 4), as I consider whether mitochondrial replacement would in fact create \u201cthree genetic parents,\u201d and whether it would even be ethically problematic if a child was born to \u201cthree genetic parents.\u201d<\/p>\n<p>&nbsp;<\/p>\n<h4>Key words<\/h4>\n<p>mitochondrial replacement, three genetic parents, mitochondrial DNA, assisted reproduction technology (ART), bioethics<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tomohide Ibuki<br \/>\nVolume 1 Issue 1 Pages 50-62<br \/>\nFirst Published: September 28, 2018<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[28],"tags":[46],"class_list":["post-153","post","type-post","status-publish","format-standard","hentry","category-translated-articles-in-english","tag-volume-1-issue-1"],"_links":{"self":[{"href":"http:\/\/cbel.jp\/en\/wp-json\/wp\/v2\/posts\/153","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/cbel.jp\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/cbel.jp\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/cbel.jp\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/cbel.jp\/en\/wp-json\/wp\/v2\/comments?post=153"}],"version-history":[{"count":1,"href":"http:\/\/cbel.jp\/en\/wp-json\/wp\/v2\/posts\/153\/revisions"}],"predecessor-version":[{"id":154,"href":"http:\/\/cbel.jp\/en\/wp-json\/wp\/v2\/posts\/153\/revisions\/154"}],"wp:attachment":[{"href":"http:\/\/cbel.jp\/en\/wp-json\/wp\/v2\/media?parent=153"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/cbel.jp\/en\/wp-json\/wp\/v2\/categories?post=153"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/cbel.jp\/en\/wp-json\/wp\/v2\/tags?post=153"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}